Cajun Garlic Baked Salmon Recipe for Flavorful Weeknight Dinner

Cajun Garlic Baked Salmon is moist, tender, and easy to prepare with minimal cleanup. This recipe bakes salmon to perfection in a buttery Cajun garlic sauce that’s full of flavor.

Salmon baked in foil

This simple salmon recipe uses common pantry ingredients and takes less than 30 minutes from start to finish. It’s a great weeknight main that feels special without any fuss. Serve with roasted vegetables or a fresh salad for a balanced meal.

How to Make Baked Salmon:

For this recipe you’ll need a 2–3 pound side of salmon, butter, garlic, Cajun seasoning, honey, lemon juice, salt, and pepper. The combination of honey, garlic, and Cajun seasoning creates a bright, savory glaze that complements the salmon’s natural richness.

  • Preheat the oven to 375°F (190°C). Line a rimmed baking sheet with aluminum foil and lightly grease or spray with nonstick cooking spray.
  • Remove the salmon from its packaging and pat it completely dry with paper towels.
  • In a small bowl, melt the butter and whisk in the minced garlic, honey, and lemon juice until combined.
  • Evenly sprinkle Cajun seasoning, salt, and pepper over the salmon.
  • Pour the butter and honey mixture over the salmon, spreading it gently so the fish is coated.
  • Fold the foil up around the salmon to form a sealed packet and place on the prepared baking sheet. Bake for 20 minutes.
  • Optional: After baking, carefully open the foil and broil for 3–5 minutes to give the top a light golden finish.

how to make baked salmon in foil

How to Tell When Salmon is Done:

Use an instant-read meat thermometer for reliable results. Salmon is considered safe and done at 145°F (63°C). You can also check doneness by flaking the fish with a fork — it should separate easily and be opaque throughout.

How to Reheat Salmon:

Salmon is best eaten fresh, but leftovers reheat well if handled gently. Reheat covered in foil at a low oven temperature (about 250°F / 120°C) for 10–15 minutes until warmed through. Leftover salmon is also delicious cold, added to salads or served with a squeeze of lemon.

baked salmon on baking sheet

Enjoy!

~Nichole

baked salmon on baking sheet
4.98 from 34 votes

Cajun Garlic Baked Salmon

By Nichole
Moist and tender salmon baked with a buttery Cajun garlic sauce for an easy, flavorful main dish.
Prep 5
Cook 20
Total 25
Servings 6

Ingredients 

  • 1 2-3 Pound Salmon Filet
  • 5 Tablespoons Butter, Melted
  • 3 Cloves Garlic, Minced
  • 1 Tablespoon Honey
  • Juice of one lemon, about 2 Tablespoons
  • 1 Tablespoon Cajun Seasoning
  • Salt & Pepper to taste
  • Parsley for garnish optional

Instructions 

  • Preheat the oven to 375°F (190°C). Line a large baking sheet with foil and lightly grease or spray with nonstick cooking spray.
  • Pat the salmon dry and place it skin-side down on the prepared foil.
  • In a small bowl, whisk together the melted butter, minced garlic, honey, and lemon juice.
  • Sprinkle the Cajun seasoning, salt, and pepper evenly over the salmon. Drizzle the butter mixture over the top.
  • Fold the foil into a packet and bake for 20 minutes, or until the salmon reaches 145°F (63°C) and flakes easily with a fork.

Notes

Cook salmon to an internal temperature of 145°F (63°C) for safe consumption. Leftovers can be reheated gently in a low oven or enjoyed cold.

Additional Info

Course: Main Course
Cuisine: American
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